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In cell lines, angiotensin IV interferes with the focal adhesion complex by causing a rapid phosphorylation of p125-focal adhesion kinase and p-68 paxillin [ 51].
The results of our study demonstrate that besides its direct cytotoxic effect on tumour cells, electrochemotherapy with BLM also has a vascular disrupting action by causing a rapid shutdown of tumour blood flow, leading to reduced tumour oxygenation, increased tumour hypoxia and extensive tumour cell necrosis.
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Dear Editor, Cerebral ischemia is characterized by the activation of glial cells, causing a rapid and massive local inflammatory reaction that leads to tissue damage and neuronal cell death.
Switching-off ERBB2 expression by tetracycline administration causes a rapid and complete tumour remission, demonstrating a high degree of 'ERBB2 dependence'.
These include a toxin produced by Staphylococcus aureus, which causes a rapid, severe, but limited gastrointestinal distress, or the toxin of Clostridium botulinum, which is often lethal.
Pressure gradients induced by stress change may cause a rapid migration of trapped soil gas.
The stripping of mass by the passing shell causes a rapid mass loss in the initial phase.
The impact of water scarcity is aggravated by the karstic geology that causes a rapid seepage of rainwater into underground drainage systems and caves.
The AR, on the contrary, is characterized by a peak of [Ca2+]i that causes a rapid and ubiquitous cascade of reactions that lead the spermatozoa to the rapid and irreversible loss of acrosome content.
First, it causes a rapid pressor response by direct vasoconstriction.
In addition, treating cells with DTT causes a rapid over oxidation of PrxIV presumably due to an acute increase in H2O2 caused by a rapid reduction of the regulatory disulphides in Ero1α and in substrate proteins.
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