Sentence examples for by causing a block from inspiring English sources

It will be of interest to assess whether Sirt1 regulates transcription of genes involved in spermatogenesis and/or alters the proportions of spermatogenic cells in the testis, perhaps by causing a block at a specific stage of spermatogenesis, in future studies.

The azoles inhibit lanosterol demethylase, encoded by ERG11, causing a block in the production of ergosterol and the accumulation of a toxic sterol produced by Erg3 (Ostrosky-Zeichner et al., 2010; Shapiro et al., 2011).

However, any more than 15 activations were prevented by structural deformations causing a block in the activation mechanism.

Lockwood and his team suggest that the sun is affecting Northern Europe by causing an increase in "blocking" of the northern jet stream, a fast-flowing river of air moving through the atmosphere.

This important miRNA is negatively regulated by the HR-HPVE7 oncoprotein causing a differentiation block [ 109].

This immuno-deficiency syndrome is characterized by the paucity of neutrophils in peripheral blood caused by a block in promyelocyte/myelocyte maturation, associated with their apoptosis.

They are thought to be caused by a block in the normal development of nephrons, as illustrated by the appearance of nephrogenic rests – structures resembling embryonic renal tissues and believed to be the first stage of Wilms' tumour development.

In the adult mice misexpression of Oct4 in epithelial tissues results in dysplasia caused by a block in progenitor differentiation [17].

It is also possible that the GFP-Atg8a and LysoTracker phenotypes are being caused by a block in the later steps of degradation, resulting in a pileup of autophagic intermediates which are formed and acidified, but fail to be destroyed.

The growth inhibitory effect of ACC inhibition was caused by a block in cell cycle progression since there was a significant reduction in the population of cells in S- and G2/M phases and a concomitant increase in cells in G0/G1 with respect to controls (Fig. 4B).

The defective operation of the urea cycle in rats fed a cafeteria diet seems to be caused by a block in the urea cycle between ornithine and arginine.