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The relationships among the radial velocity of the particle, the particle size, and the friction coefficient of the rock were obtained by calculating the model.
The deviation between the toxicity predicted by CA and the observed toxicity of the combination product was quantified by calculating the model deviation ratio (MDR) that had been introduced by Belden et al. [15].
The patient's liver function was characterized at baseline immediately before the beginning of each CVVHD treatment by calculating the Model of End-stage Liver Disease score [ 13], the Child-Pugh score [ 14] in case of cirrhosis, and by determining laboratory liver function parameters (aspartate aminotransferase, alanine aminotransferase, bilirubin, cholinesterase, prothrombin time).
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We further evaluated glucose homeostasis by calculating the homeostasis model of insulin resistance (HOMA-IR) index and by performing glucose and insulin tolerance tests (ITTs).
Similar results were also obtained by calculating the hybrid model for the slab with the DE solution for the infinite medium.
Insulin resistance was assessed by calculating the homeostasis model assessment of insulin resistance and the quantitative insulin sensitivity check index as previously described [ 23, 24].
Insulin resistance was measured by calculating the homoeostasis model assessment (HOMA) index as follows: fasting insulin (μIU/mL) × fasting glucose (mg/dL)/405 [ 38].
Insulin sensitivity was assessed by calculating the Homeostasis Model Assessment Insulin Resistance (HOMA IR) and Quantitative Insulin Sensitivity Check Index (QUICKI), as previously described [ 23, 24].
Estimate the translation between the models by calculating the difference between the models' centroids.
The two treatment strategies were evaluated with the model by calculating the incremental cost-effectiveness ratio.
We took into account the familial correlation in the model by calculating the robust variance.
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