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It provides a statistical framework to evaluate how well the MLSA data fits the non-sequence-based phylogenies by calculating a likelihood value associated with each of the methods.
All the tests for α and β can be performed by calculating a likelihood ratio statistic which asymptotically follows a chi-square distribution with the corresponding degrees of freedom.
We identified SNPs for the haploid strains and heterozygous sites for the diploid strains by calculating a likelihood ratio statistic.
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Branch support was estimated using 100 bootstrap replicates, and by calculating an approximate likelihood-ratio test [ 90].
To determine over-represented TFBS motifs, Clover starts for every location in a DNA sequence, by calculating a score reflecting the likelihood that a certain TF binds at that location.
Adjustment for these covariates was performed by calculating a propensity score, which reflected the likelihood that an individual patient was prescribed an anti-TNF given their known characteristics.
STRUCTURE implements a Bayesian algorithm to assign multilocus genotypes to genetic clusters by calculating the likelihood that a group of individuals constitutes a population.
We determine the probability-density function by calculating from edge likelihood and silhouette likelihood, as explained in Section 2.2.1 and Section 2.2.2, respectively.
The likelihood of over-treatment with antibiotics associated with each management strategy was determined by calculating the likelihood that patients without Group A streptococcal infections would be treated.
We determined under-treatment with antibiotics by calculating the likelihood that patients with Group A streptococcal infections would not be treated under each management strategy.
In our HMM framework, we do this by calculating the likelihood p(D | Θ), which is the probability that a dataset D of MD simulation trajectories occur under the model Θ.
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