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These advances have been informed by both direct analysis of the post-mortem brain and by study of the biological consequences of the genetic causes of these diseases.
The body postures assumed at the time of PDC emplacement were assessed by both direct analysis of casts and skeletons as well as by archive photographs, to search for evidence of PDCs lethal effects caused by mechanical impact, heat exposure and dusty gas inhalation in victims found inside as well outside buildings.
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This resource will be key to the continued evaluation of karyotypic abnormalities in canine malignancies, whether by CGH analysis or by direct analysis of tumour metaphases.
It is quite difficult to determine the probability of Peter's ruin by a direct analysis of all possible cases.
The feasibility of the system was demonstrated by the direct analysis of three auxins from different plant tissues, including leaves of Dracaena sanderiana, buds and petals of Bauhinia.
On the other hand, the macroscopic adhesive behaviour is obtained by a direct analysis of the two-distinguished phases interaction at the microscopic level, using micromechanics and homogenization.
Gene disruption in vivo for gene-trap mutations was confirmed by a direct analysis of gene expression using RT-PCR.
Another is altered localisation characterised by the direct analysis of tissue sections with methods such as MALDI imaging mass spectrometry (IMS) (Caprioli, 2005).
DUBs generated by IVT were incubated with each of these three probes (Figure 2), followed by direct analysis of the reaction mixture by SDS-PAGE.
The potential of GTI detection by direct analysis was recently demonstrated in 2011 by McCullough et al., using online extractive electrospray (EESI) sampling from a heated reaction mixture, where codeine was used as a surrogate GTI.
Alleles containing between 5 and 100 to 125 CTG-repeat units can be detected and characterized using synthetic fluorescently-labeled primers flanking the CTG-repeat region, followed by direct analysis of the length of the amplified products by capillary electrophoresis.
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