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The VEGF and COX-2 mRNAs were identified as the bona fide targets of miR-101 in cholangiocarcinoma cells by both computational analysis and experimental assays.
Our experimental data from microarray is supported by both computational analysis and literature searches, where differentially expressed gene signatures are shown to promote the malignant CRC process.
The widely known argument about the report of a plant G-protein coupled receptor [ 1], which subsequently was suggested to be a cytoplasmic lanthionine synthetase-like protein by both computational analysis and experimental verification [ 2, 3], illustrates the value of sequence analysis.
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By computational analysis, we showed that both the hTectonin and GBP form β-propeller structures with multiple Tectonin domains, each containing β-sheets of 4 strands per β-sheet.
Several of these had not had both mate-pair BES available previously and hence would have been undetectable by our computational analysis.
When information regarding genomic sequences is not rich, InDels polymorphism of tetraploid cotton species obtained by computational analysis might include both homologous and homoeologous loci variation.
The mechanical properties of suspended DNA bundles change in a measurable way as a function of the type and mode the molecules interact with it, as also predicted at molecular level by our computational analysis.
By a computational analysis of sequence data, we examined patterns of variability in light of the seasonality of flu outbreaks.
Four of these categories comprise exclusively manually-curated associations supported by experimental, computational analysis, author statements or curatorial statements.
The fundamental role of the PI3K pathway in ESCs, as suggested by the computational analysis, is supported by different lines of experimental evidence.
HNRNPH1 and CLK1, two trans-acting splicing regulator factors, are predicted by our computational analysis to be differentially spliced between tumor cells.
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