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Standard errors of Ks and Ka were obtained by bootstrap resampling with 500 pseudoreplicates.
The tree was tested by Bootstrap resampling with 1,000 replications and displayed rooted at the midpoint.
(18, 19) Point-wise 95% confidence intervals (CI) for the relative hazard have been calculated by bootstrap resampling with 1000 repetitions.
Statistical support was estimated by Bootstrap resampling with 100 pseudo-replicates generated by the program SeqBoot of the PHYLIP package [ 71].
Statistical support for the nodes was obtained by Bootstrap resampling with 100 pseudo-replicates generated by the program SeqBoot 3.5 of the PHYLIP package [ 69].
Comparisons of mortality were performed using conditional fixed-effects Poisson regression with 95% confidence intervals (CIs) estimated by bootstrap resampling with 500 replications (effect estimate: matched groups relative risk) [ 22].
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Multiple testing was corrected by bootstrap resampling technique with 1000 resamples and a FWER = 0.05.
Branch support was examined by bootstrap resampling [ 33] with 100 replicates.
The phylogenetic relationship was constructed by the neighbor-joining method using MEGA 5.1 from the evolutionary distance data corrected by a two-parameter model developed by Kumar [ 16], and evaluated by bootstrap resampling [ 17] with 1,000 replicates.
Sequence sharing in tC versus tCI comparisons was both greater than in reshuffled datasets (mean = 66.4±15.0%; n = 240 movie pairs; reshuffled mean = 44.6±0.3%; different with p<0.001) and was not different from in tC versus tC comparisons (67.5±13.6%, n = 165 movie pairs; not different with p>0.10 by bootstrap resampling) (Figure S2b).
Also, sequence sharing in sC versus sCI comparisons was both greater than in reshuffled datasets (mean = 60.9±20.2%; n = 135 movie pairs; reshuffled mean = 49.6±0.7%; different with p<0.001) and was not different from in sC versus sC comparisons (60.7±18.8%, n = 67 movie pairs; not different with p>0.10 by bootstrap resampling) (Figure S2a).
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