Sentence examples for by blocking the synthesis from inspiring English sources

In cutaneous T-cell lymphoma (CTCL), MTX increases Fas death receptor by decreasing Fas promoter methylation by blocking the synthesis of SAM, the principal methyl donor for DNMTs, resulting in enhanced Fas-mediated apoptosis.

Triclosan works specifically by inhibiting the active site of the enoyl-acyl carrier protein reductase enzyme (ENR) which is an essential enzyme in fatty acid synthesis required for building cell membranes and lipid production in the microbe by blocking the synthesis of lipids (Annis 2012; Dorugade and Bhagyashri 2010; Gao and Cranston 2008; Purvar and Joshi 2004).

The apparent lack of a transaldolase homolog in the PPP may have effects on the organisms' ability to respond to oxidative damage (discussed above), but may also limit an alternative mode for ATP production via glycolysis by blocking the synthesis of F6P and GAP.

This process can be easily induced by adding physiological concentrations of T3 to premetamorphic tadpole rearing water or prevented by blocking the synthesis of endogenous T3.

At this chronic stage, urate deposits built up over decades are only slowly depleted by blocking the synthesis of urate, particularly because the renal clearance of urate is often inefficient in these patients.

Besides their role in cartilage degradation by stimulating MMPs, IL-1β and TNFα impair the ability of the cartilage to restore the extracellular matrix by blocking the synthesis of new extracellular matrix components [ 3].

The yield of fatty alcohol in cyanobacteria was then increased to approximately 761 ug/g dry mass by blocking the glycogen synthesis and poly-3-hydroxybutyrate (PHB) synthesis as well as by over-expressing the FAR genes [ 39].

Paromomycin otherwise inhibits cell growth by blocking the protein synthesis of ribosomes at the translocation stage [ 32].

Blocking the synthesis of ceramide by inhibiting ASM introduced new therapy options for the treatment of the above mentioned diseases.

22 Reports from, in vivo and in vitro studies have demonstrated a reduction in cell proliferation in various cancers including RB by blocking the HMGA2 protein synthesis using antisense methodology.

NSAIDs exert their principal therapeutic effects, reducing fever, pain and inflammation, by blocking the cyclooxygenase (COX -mediated synthesis of inflammatory prostaglandins [ 18].