Sentence examples for by blocking the integrin from inspiring English sources

By blocking the integrin receptors α1, α2, and β1 a decrease in cell growth was observed.

This mode of activation provides another possible pathway for regulating myofibroblast activity by blocking integrin binding to latent TGF-β1, for example by blocking the integrin involved in latent TGF-β1 activation, αvβ5.

In this study, it was found that rhFNHN29 and rhFNHC36 inhibit MHCC97H cell adhesion and invasion by blocking the integrin-FAK-AP-1 pathway.

It was found that the induction of TSP-1, which is a TGF-β regulated gene only in A549 cells, is affected by blocking the integrin-linked signalling pathway.

In addition, the osteogenic conduction by β-TCP scaffolds was attenuated directly by inhibiting MAPK/ERK or indirectly by blocking the α2β1 integrin signaling pathway.

Wild-type HIEC cells adhered efficiently to this RGD-containing domain, and adhesion was completely abolished in the presence of a soluble RGD-containing peptide (results not shown) or by blocking the β1 integrin subunit.

For gastric cancer cells, peritoneal invasion was inhibited by blocking the collagen I-binding integrin α2β1 [ 44].

In summary we concluded that, since the enhanced motility of Panc-1 cells on FAP+ 3D matrices can be significantly reversed by blocking the function of β1-integrins, a potential mechanism of matrix mediated tumor invasion is an attractive possibility.

We used a novel xenograft mouse model to directly determine if bone pain could be prevented by blocking the known cleavage of the A6 integrin adhesion receptor.

The induction of Integrin αV is partially affected by blocking the JNK pathway (Fig. 5).

Neutralizing antibodies of integrin were used to block the integrin signaling pathway.