Sentence examples for by blocking the generation from inspiring English sources

In addition, FGF-23 acts as a counter-regulatory hormone for vitamin D by blocking the generation of 1,25(OH)2D both through inhibition of the renal 1 α-hydroxylase enzyme and through the stimulation of the 24-hydroxylase enzyme that is responsible for the degradation of both the 25(OH D and 1,25(OH)2D metabolites [ 87].

Blocking the generation of prostaglandins by celecoxib (Celebrex) prevented the increased secretion of NGF by tooth perfusates in rats after an inflammatory stress [ 56].

SCEE may give cell protection by hindering CCl4-mediated lipid peroxidation, hence blocking the generation of free radical derivatives [ 49].

Linagliptin could exert beneficial effects on diabetic nephropathy partly by blocking the AG Es-RAGE-evokedoxidative stress generation in the kidney of streptozotocin-induced diabetic rats.

NP can catalyze the O2− generation either by blocking the electron transport chain or accelerating electron transfer to molecular oxygen [ 54, 55].

So, linagliptin might inhibit the AGE-evoked inflammatory and thrombogenic responses in HUVECs by blocking the positive feedback loops between ROS generation and RAGE gene up-regulation.

18 Under the pathophysiological point of view, there are two approaches to treat acute angioedema, including emergent therapies: to replace C1-INH and to inhibit bradykinin generation either by blocking the enzyme kallikrein or preventing the interaction of bradykinin with its receptor.

Thus, knockdown of Myc prevents CMS sensitization to TRAIL by blocking the decrease in FLIPL levels, which ultimately inhibits generation of active p18 caspase-8.

10.7554/eLife.09262.007 Figure 4. Spontaneous Ca2+ transient generation is decreased by blocking release of Ca2+ release from internal stores but not by blocking the AMPA receptors, L-type Ca2+ channels or group I mGluRs.

Studies with cancer stem cells have shown that inhibition of mTOR pathways by rapamycin can block the generation or maintenance of leukemia-initiating cells in the PTEN-deficient mice.

Strikingly, overexpression of both CdgB and YhjH blocked the generation of aerial mycelium by S. venezuelae.