Sentence examples for by blocking the function from inspiring English sources
In fact, the finding has raised the question of whether insomnia medications that work by blocking the function of the orexin receptor could harm the heart, although this has not yet been studied, Perez said.
Lysosomal inhibitors can also increase the number of autophagosomes by blocking the function of lysosomal protease (Fig. S3F and S3G), but result in slightly reduced dendritic lengths (Fig. 4J).
Levamisole temporarily suppresses muscular activity by blocking the function of nicotinic acetylcholine receptors (nAChR), while NaN3 inhibits both cytochrome c oxidase and adenosine triphosphate (ATP) synthase.
Inhibition of viral gene expression by inhibitors that block later stages of the viral life cycle (e.g. by blocking the function of viral proteins such as Tat or Rev) will not prevent transduced cells from becoming infected, while inhibitors that block early events in the viral life cycle prior to integration can prevent infection.
They often act by blocking the function of their target molecule.
Therapeutic antibodies work by blocking the function of proteins, the end products of the gene-mRNA-protein cascade.
Recent studies have shown that nilotinib induces potent sensitization to anticancer agents by blocking the functions of ABCB1/P-glycoprotein (P-gp) in multidrug resistance (MDR).
These observations confirmed that TDG, as a single agent, inhibited tumor angiogenesis by blocking the functions of galectin-1 in promoting EC growth and survival and blood flow in our tumor models and presumably would do so in other tumors.
Therefore, it would be desirable to design therapeutic drugs that function by permanently blocking the function of the target gene at the DNA level.
These results indicate that nilotinib reverses P-gp- mediated MDR by blocking the efflux function and potentiates DOX-induced cardiotoxicity.
Overall, our results indicate that nilotinib could reverse ABCB1- and ABCG2-mediated MDR by blocking the efflux function of these transporters.
