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The rice DELLA protein is stable in the absence of GA ensuring that transcription of GA-early responsive genes are repressed by blocking the activity of a transcriptional activator bound to the promoters of target genes.
In fact EGCG, vitamin C and selenium inhibited the activation of NF-κB by blocking the activity of IKK [ 23, 24].
The available literature suggests that ibuprofen inhibits the activation of NF-κB by blocking the activity of phosphorylating kinases IκB [ 32].
Rac1 via activation of the p21-activated kinase (PAK) antagonizes this process by blocking the activity of myosin light chain kinase.
The most-well-known role of BUBR1 is as a component of the mitotic SAC, which, when activated, prevents cells from entering anaphase by blocking the activity of the APC/CCDC20 ubiquitin ligase (Jia et al. 2013).
Key lineage transcription factors work in combination with co-factor complexes both through the activation or silencing of lineage-specific genes and concomitantly by blocking the activity of competing transcription factors of other lineages.
Similar(18)
Tag provides the driving force for tumor initiation by blocking the activities of Rb and p53 tumor suppressors [27].
Transition to cell-cycle progression is achieved by blocking the activities of the cell-cycle repressors.
Recent attention has focused on targeting the cyclooxygenase 2 (COX-2) pathway downstream of the COX-2 enzyme by blocking the activities of individual prostaglandin E (EP) receptors.
Six FDA-approved drugs are currently in clinical use, all designed to inhibit enzyme activity by blocking the active site, which exists only in the dimer.
Mifepristone is known to exert anti-progestin activity by blocking the action of progesterone on progesterone receptors (PR) [ 34].
More suggestions(16)
by blocking the lymph
by blocking the merger
by blocking the renin-angiotensin-aldosterone
by examining the activity
by blocking the proliferation
by blocking the surface
by blocking the bill
by blocking the downstream
by increasing the activity
by regulating the activity
by blocking the market
by blocking the noradrenaline
by blocking the induction
by blocking the intestine
by blocking the growth
by blocking the uptake
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com