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Other examples indicate that lncRNA transcription activates gene expression by blocking access of repressor complexes to chromatin.
DAPT would then act as an inhibitor by blocking access of the substrate to the active site.
Furthermore, hysterectomy may reduce ovarian cancer development by blocking access of ovarian carcinogens that enter the peritoneal cavity via the vagina (4).
In the case of human DHFR, the "PEKN" insertion generates specificity by blocking access of the dihydrophthalazine to the binding site, but in Ef DHFR, the effect on a single insertion is translated to the cofactor site.
Direct binding of NF-κB1 p105 to the TPL-2 kinase domain also negatively regulates TPL-2 MKK (MAPK kinase) 1/2 activity by blocking access of MKK1/2 to its active site [ 5, 8].
The year-round and long-term data, obtained by blocking access of flies to broiler houses, indicate that flies are responsible for a major part of the Campylobacter spp. positivity among broiler chicken flocks during the peak season, June October.
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He said he tried to install a spam filtering program -- as 37percentt of those in the Pew survey with personal e-mail accounts have done -- but found that it created more problems by blocking access to a good deal of legitimate e-mail.
He added that because of the encryption technology used by the three firms, Russia had no way of blocking specific websites and so could only bring down particular content it deemed in violation of law by blocking access to their whole services.
Big media made sure of it by blocking access to their online streaming, seemingly taking away Google TV's most novel feature.
Authoritarian regimes can exert old-fashioned mind control by blocking access to the internet and robbing citizens of opportunities to speak beyond their own borders.
In the case of the SeCobA ACAT, crystallographic and kinetic studies have revealed that the phenylalanine 91 (F91) and tryptophan 93 (W93) residues are critical for in vivo activity, presumably by blocking access to the lower axial ligand site of the Co II)rrinoid substrate.
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by blocking movement of
by blocking reform of
by modulating access of
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by blocking delivery of
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by blocking elongation of
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by blocking inflow of
by blocking construction of
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com