Sentence examples for by blocking a channel from inspiring English sources

HDIs inhibit HDAC activity by blocking a channel that leads to the active site and a catalytic zinc ion [ 11].

This revealed that bradykinin sensitizes the motor nerves by blocking a type of potassium ion channel and activating another ion channel that mainly transports sodium ions.

Selamectin works by blocking a particular type of ion channel in flatworms, but this ion channel is not found in vertebrates, which means that selamectin must be promoting the formation of neurons in mice via a different mechanism.

By blocking the channel with nifedipine, a clear selective decrease in the contraction force of the different muscles studied was observed (Fig. 3).

Thus, there is a logical basis for targeting this, and central neuronal excitability, by blocking sodium channel function to reduce action potential generation and transmission.

α-Toxins from scorpion venoms prolong the action potential of excitable cells by blocking sodium channel inactivation.

We showed that the invasion and transendothelial migration of breast cancer cells can be attenuated by blocking BKCa channel activity.

It phosphorylates Bad and ultimately inhibits Cyt c release by blocking the channel formed by Bcl-2-associated X protein (Bax) in the mitochondrial membrane [ 54].

Here we found that SD inhibits Kv1.3-mediated currents in Jurkat T cells, and further demonstrated that its essential active component LrB directly suppresses Kv1.3 by blocking the channel pore, thereby inhibiting the release of IL-2.

As knockdown of the TRPM7 channel reduces the pathogenesis of brain ischemia, it is tempting to speculate that 5-LO Xinhibitors achieve a portion of their cellular protective effects by blocking the TRPM7 channel.

This is for most people an explanation at least as comprehensible and rational as being told that they work by blocking the potassium channel or selectively inhibiting serotonin reuptake.