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This could be dramatically suppressed by blockade of C5a in the lung or depletion of either neutrophils or alveolar macrophages.
Inhibition of ECM protein receptors by blockade of β1 integrins suppressed astrocyte responses to ECM components [15].
Lastly graft rejection can be reduced by blockade of the B7/CD28 costimulation pathway with the fusion protein CTLA-4Ig.
However, hypoxic injury was prevented by blockade of voltage-gated sodium channels, inhibition of calpain and removal of extracellular calcium.
Therefore, therapeutic strategies for SSc and some other fibrotic disorders may be designed by blockade of HSP47 expression, the downstream effector of TGF-β signaling, to ameliorate fibrosis.
Disease was prevented only by blockade of the endothelial adhesion molecule, ligand of homing receptors with which the T cells were imprinted.
The sinus nerve responses to H2S donors were prevented by blockade of the transmission between type I cells and the afferent terminals, as was the response to hypoxia.
Similar effects were obtained by blockade of inhibitory Ly49 receptors in TRAMP mice.
Inhibition of early platelet adhesion by blockade of glycoprotein-IB (GPIb) protects mice from ischemic stroke.
Antiangiogenic treatment by blockade of VEGFR2 but not VEGFR1 may limit adipose tissue expansion.
We show that olfactory interference can be disrupted by blockade of cimetidine-sensitive pathways specifically in the deuterocerebrum.
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