Sentence examples for by binding to different from inspiring English sources
ERα and ERβ regulate different genes by binding to different regulatory elements and recruiting different transcription and chromatin remodeling factors that are expressed in a cell-specific manner.
Maximal spore heat and nitrite resistance required production of all four C. perfringens Ssps, indicating that these Ssps act cooperatively to protect the spore's DNA, perhaps by binding to different chromosomal sequences.
Hsp70 is able to modulate the immune system by binding to different cell surface receptors, including Toll-like receptors (TLRs) that are known to activate NF-κB [33], [36], [37], and CD40 leading to the activation of p38 MAP kinase [44].
Results also show that unstructured post-translationally modified C-terminal tails are responsible for the dynamics of Sm-B/B' and U1-C and that their interactions with the Sm core are controlled by binding to different U1-70k isoforms and their phosphorylation status in vivo.
p75NTR regulates neuronal survival and death by binding to different ligands and signaling co-receptors.
14-3-3 14-3-3 14-3-3 14-3-3nt cell death by binding to different proteinstoticouldteins.
A group of 55 clones represented by 13 mAbs with a unique V(D J recombination were characterised by strong binding to different H5 rHA antigenic formats (data not shown) and in vitro neutralizing activity (Table 2).
In biological assays, the antigen-binding activity of the re-natured protein, TfRscFv-GAL4, was confirmed by specific binding to different cancer cells and tumor tissues.
By simultaneously binding to different cell surface targets, BsAb may result in enhanced binding avidity, leading to preferential (strong) binding to only cells that express both targets but not cells that only express a single target, thus fine-tuning the antibody selectivity [54].
To examine whether the differential effects of these IgG may be explained by their binding to different epitopes of the FXa active site, we compared the effects of APS-IgG, SLE-IgG and a 50/50 mix of these upon FXa activity to examine whether an appreciable increase in ability to inhibit FXa activity would be observed with the mixed APS/SLE-IgG samples.
They are distinguished from one other by their preferential binding to different melanocortin receptors (MCRs), through which they exert their effects, and by their structure, with each arising from a different region of POMC.
