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The kinase itself works by binding to certain receptors on the surfaces of cells, leading to a cascade of molecular changes that are all aimed at instructing the cell to keep dividing and growing, uncontrollably.
Alteration of cellular functions by binding to certain thiol groups of biomolecules is the most commonly invoked pathway for Cd toxicity (Joseph 2009).
Folding into the correct shape is crucial for a protein to function properly because many proteins work by binding to certain other proteins or molecules, like a key fitting into a lock.
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The initial step in mucosal infection by the herpes simplex virus type 2 (HSV-2) requires its binding to certain glycosaminoglycans naturally present on host cell membranes.
This simple modification dramatically improved selective binding to certain G-quadruplexes.
Further, PARP1 binding to certain substrates and their recruitment to DNA damage lesions is impaired by TIMELESS knockdown, and TIMELESS silencing significantly impairs DNA double-strand break repair.
TGF-β inhibits the expression of MMP-1 and MMP-3 by binding to a certain cell surface receptor complex (TGF-β receptor proteins: TβR I/II/III), thus preventing the breakdown of collagens.
It codes for a protein known as a transcriptional activator, which drives the expression of other genes by binding to DNA and certain proteins involved in transcription.
This protein helps modulate the transcription of certain genes by binding to a specific sequence on the DNA after it has been activated by phosphorylation.
The new findings suggest that the three chemokines suppress HIV replication by binding to the same receptors needed by certain strains of HIV to enter immune cells.
Among the most promising, he says, is an antibody that blocks communication between certain immune cells by binding to a receptor on their surface called CD40.
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