Sentence examples for by binding the complement from inspiring English sources

SpA can prevent phagocytosis by binding the complement binding portion (Fcγ) of functional antibodies thus hindering the antibody binding to bacterial cell surface components and subsequent complement dependent uptake of bacteria by phagocytic cells.

The fact that B. burgdorferi can cause a chronic infection is based on the ability of the bacterium to escape complement-mediated opsonophagocytosis by binding the complement inhibitor factor H (and in some cases, also the factor H-like protein 1) to its surface.

Since in this work it has also been shown that PfGAP50 may protect the gametes from complement-mediated lysis by binding the human complement Factor H, the protein can be regarded as novel transmission-blocking candidate.

CD59 functions by binding the C5b678 terminal complement protein complex and preventing the incorporation of the multiple C9 molecules required to complete the formation of a pore in the cell membrane [13].

CD46 regulates complement activation by binding the C3b and C4b complement products deposited on host cell membranes and serves as a cofactor for their proteolytic inactivation by the plasma serine protease factor I. This process, which irreversibly prevents C3 and C5 convertase formation, protects host cells from lysis by autologous complementation [ 19].

To explain this discrepancy we hypothesized that complement activation could enhance RBC invasion by binding to the complement receptor 1 (CR1).

Afa/Dr adhesins mediate bacterial attachment onto target cells by binding to the complement regulatory glycosylphophatidylinositol- GPI- anchored protein DAF [ 166].

Furthermore, iC3b can opsonize Leishmania and allow entry in the host cell by binding the receptors CR1 and CR3 (complement receptors) [ 161, 162].

Neu5Ac is a negatively charged 9-cabon sugar that inhibits complement, in part by enhancing binding of the complement inhibitor factor H (FH) through C-terminal domains (19 and 20) on FH.

For example, human pathogenic fungi Aspergillus fumigatus and Candida albicans evade immune attack by binding complement regulators in order to suppress complement effector molecules [31].

However, a wide variety of pathogens subvert complement attack by binding host complement inhibitors, which results in diminished opsonophagocytosis and killing of bacteria by lysis.