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The virus-type is the strategy by binding a protein to its gene [ 10, 11].
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Although both alleles bind a transcriptional activator, the 5G allele reduces transcription by binding a repressor protein, and is associated with lower circulating plasminogen activator inhibitor-1 concentrations [ 16, 17].
Kinases are turned on or off by phosphorylation (sometimes by the kinase itself), by binding an activator protein, an inhibitor protein, or small molecules.
Our results indicate that hsp70 interferes with Akt phosphorylation by binding an upstream protein of the Akt signaling pathway in RA FLSs.
In one study of positive feedback, massive introduction of tandem-repeat "Decoy" DNA sequences decreased expression in living yeast by binding an activator protein, and also altered the inhibitory effect of a small molecule on the activator [ 6].
Although the exact mechanism of Ku-mediated telomerase recruitment remains unclear, a simple model is that Ku recruits telomerase to telomeres by binding a telomere-bound protein.
DNA polymerase V is activated by binding to a protein called RecA and a molecule of adenosine triphosphate (ATP for short).
Erivedge works to inhibit the so-called Hedgehog signaling pathway by binding to a protein called Smoothened.
The question is, why?PCBs do their damage by binding to a protein called the aryl hydrocarbon receptor, or AHR, thus stopping it working properly.
Pyrethroids are axonic poisons that affect the nerve fiber by binding to a protein that regulates the voltage-gated sodium channel.
The lectin pathway of complement system is initiated by binding of a protein complex consisting of mannose-binding lectin (MBL) and serine proteases, mannose-binding lectin associated proteases 1 and 2 (MASP-1 and -2) to mannans on bacterial cell surfaces, and thus its activation is independent of antibody like alternative pathway.
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