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Patients' baseline characteristics, echocardiographic parameters and rest/stress haemodynamics are stratified by baseline diastolic function and shown in tables 1– 3, respectively.
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Routine exercise stress echocardiogram therefore should remain a valid tool in the care of patients with HCM irrespective of baseline diastolic function to assess their functional capacity.
Baseline diastolic function was not an independent predictor of functional exercise capacity or maximal MET achieved (p=0.9; table 4).
MEASUREMENTS AND MAIN RESULTS: Baseline diastolic function was graded according to a predefined Doppler-based algorithm, which defined LVDD as a binary variable (grades 2 and 3 only) and as a continuous variable (E/e' ratio).
This study sought to assess the relationship between baseline diastolic function and exercise capacity in patients with HCM.
Routine treadmill exercise stress echocardiogram should be performed in patients with HCM when clinically indicated irrespective of baseline diastolic function.
At present, however, it is premature to make recommendations about when, how often and which selection of diabetic patients should be imaged to assess baseline diastolic function.
After adjusting for these confounders and other relevant ones (table 4), baseline diastolic function was not an independent predictor of maximal METs achieved.
This is the largest study to our knowledge that evaluated the association between baseline diastolic function and exercise capacity in patients with HCM.
The pattern of flow is modified by left ventricular diastolic function [ 1].
Assessment of baseline cardiac systolic and diastolic function as well as cardiac LV geometry was performed by echocardiography.
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