In addition, BPI can also result in a reduction in the levels of stress and/or discomfort experienced by experimental animals by avoiding the need for invasive sampling procedures routinely used to determine the bacterial load in specific tissues or fluids such as blood or the cerebrospinal fluid (Kadurugamuwa et al., 2005c).
This minimizes the probability of methodological errors and improves sample quality by avoiding the use of previously thawed samples [23].
"You can save money by reducing the need for lab equipment and personnel, and save time by avoiding the need to transport samples, clean and prepare diagnostic equipment, conduct the analysis, and write up reports.
This highly standardized procedure minimizes the probability of preanalytical errors and also makes possible the use of high quality samples on every occasion by avoiding the use of previously thawed samples.
Joint clustering constrains all samples to the same consensus clusters, allowing rigorous comparison between samples by avoiding the problem of alternate clustering solutions.
By avoiding the solvent extraction of wood samples, enzymes could be screened on more commercially relevant feedstocks and enzymes resistant to wood extractives could also be discovered.
Using a tandem mass spectrometer in which the mass analysers act as two mass filters, one for the peptide molecular ion mass and the other for a known sequence fragment, SRM-MS provides a selectivity and specificity that in many cases enables one to simplify sample preparation by avoiding the initial immunoprecipitation or fractionation common in many other mass spectrometry-based strategies.
Previous work by Brookes et al [ 21, 41] has demonstrated how subgroup analyses that utilize continuous independent variables and examine interaction terms can produce substantial improvements in statistical power, since such analytic approaches better utilize the full sample size of the study by avoiding dividing the sample up into discrete subgroups[ 22].
(With higher substrate concentrations, we could avoid the sample handling problem by assaying the same volume of each dilution, but the same approach with more dilute substrate would yield samples with no counts).
