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The chief characteristic of a task to be formulated as a crowdsourcing job is that it cannot be solved by automated computational methods.
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Central to our strategy is the rational engineering of residues within and proximal to CDRs and the VH/VL interface by iteratively exploring substitutions to the closest human germline sequences using semi-automated computational methods.
Predicted bovine NCBI transcripts are generally derived by automated computational analysis using the NCBI gene prediction method GNOMON (http://www.ncbi.nlm.nih.gov/genome/guide/gnomon.shtml).shtml
Based on sequence comparison with human TNRC9, we believe that this represents an error generated by automated computational analysis.
The majority of those unalignable expressed RefSeq genes are previously predicted by automated computational analysis with unknown functions, suggesting they have not been well studied yet.
Here we present an easy to use semi-automated computational method for determining lesion volume and location, designed to increase precision and reduce the manual labor required.
In this work, we presented a fully automated-computational-method to analyze high-resolution microarrays measurements of nucleosomal occupancy along the genome.
This is achieved by embedding advanced computational methods for noise prediction within automated and semi-automated optimisation schemes.
By uploading analyses generated by the computational methods they develop, bioinformatics developers will potentially reach out to more users unfamiliar with their tools.
These experimental techniques have been joined by advances in computational methods such as molecular mechanics, whereby the total strain energies of various conformations are calculated and compared (see also chemical bonding: Computational approaches to molecular structure).
Protein interactions predicted by computational methods are even noisier.
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