Sentence examples for by attenuating the function from inspiring English sources
Talebizadeh et al. [63] hypothesized that the disease-associated human isoforms could play a regulatory role by attenuating the function of the full-length isoform.
Such molecules, including truncated forms of neurexin I and neuroligin (i.e. mimicking autism variants, missing EF metal binding motifs), could serve regulatory roles by attenuating the function of full-length isoforms or behave as soluble signalling molecules [63], [70].
The CD4+CD25− T-cell-derivedGITR+ cells (GITR+ non-Treg) are also known to activate self-reactive T cells by attenuating the function of Tregs, indicating that they may harm the living cells by eliciting autoimmunity.
Our findings suggest that PF4 or the p17-70 fralsont alsuppressesses VEGF function by attenuating the production of this potent proangiogenic factor.
Additionally, metformin, the most frequently used antidiabetic drug, inhibits cell migration and invasion by attenuating the cancer stem cell (CSC) function mediated by deregulating miRNAs including let-7a, let-7b, miR-26a, miR-101, miR-200b, and miR-200c, which are typically lost in PC [ 69].
It also has a regulatory function limiting the accumulation and activity of neutrophils by attenuating the anti-apoptotic effect of inflammatory cytokines during the inflammatory process [ 50].
By attenuating the flash using the LCD, a variety of illumination effects can be achieved.
Finally, we observed that downregulation of transcription factors and mating pathway components by attenuating Hsp90 function led to decreased target gene expression and pheromone response, respectively, providing a direct link between observed proteome regulation and cellular phenotypes.
It has been noted that cells with overexpressed gelsolin have a prolonged S phase followed by a delay in G2, suggesting that downregulation of gelsolin may lead to malignant transformation by attenuating G2 checkpoint function (Sakai et al, 1999).
Using the incentive runway, it was shown that mice made hyperdopaminergic by genetically attenuating the dopamine transporter (DAT) function found the goal box significantly faster than wild-type mice.
