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To be able to consider the radiation within the aerothermoelastic simulation, the structural solver is extended by appropriate computational methods.
Samples or features with too many missing values should be excluded while the rest can be imputed by appropriate computational methods that best suit the experimental data of interest, including replacement by a small value that is half of the minimum positive value in the input data table, mean or median, k-nearest neighbor, probabilistic principal component analysis and others.
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Chromatin immunoprecipitiation followed by sequencing (ChIP-seq) is a technique that provides genome-wide occupancy data of these modified histone proteins, and it requires appropriate computational methods.
Ideally, the computational signal detection workflow in this case would first require mapping the analysis requirements defined by stakeholders (step 1) to the appropriate datasets and computational methods, and then (upon selection) launching the analysis (step 2).
Among the hundreds of genes encoding miRNAs in plants reported, much more were predicted by numerous computational methods.
To benchmark the predictions obtained by different computational methods we used both "Cost Curves" and ROC analyses.
These results were corroborated by other computational methods (see the Supporting Information for details).
For experimental validation, true positives (TPs) were defined as CNVs which were detected by computational methods and confirmed by exaCGH.
The empirical claim is that all fundamental physical magnitudes and their state transitions are such as to be exactly described by an appropriate computational formalism — without resorting to the approximations that are a staple of standard computational modeling.
Protein interactions predicted by computational methods are even noisier.
Predicting off-targets by computational methods is getting increasing importance in early drug discovery stages.
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