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Significant differential expression was calculated using the Beadstudio software by applying multiple testing corrections using Benjamini and Hochberg False Discovery Rate (FDR) [28], [29].
The false discovery rate (FDR) is controlled by applying multiple testing corrections to the cytosine level tests within each region.
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We applied multiple testing corrections.
Also, by applying multiple comparison tests for statistical analysis of all differences among means of the other parameters at the same year, which included photosynthetic parameters, proportional of photosynthetic pigment, sucrose metabolism, and protein hydrolysates.
The predictors were optimized for performance by applying multiple t-tests with a cut-off probability value of 0.01 using statistical package R[25] (version 2.5.1).
By applying multiple regression analysis to the test results, a second-order polynomial equation (5) was obtained in order to represent lipid content as a function of glucose concentration, ammonium tartrate concentration, and harvesting time.
By applying multiple regression analysis to the test results, a second-order polynomial equation (3) was derived to represent biomass as a function of glucose concentration, nitrogen concentration, and harvesting time: (3) Y = 20.73 + 0.19 X 1 + 1.70 X 2 + 0.04 X 3 − 0.72 X 1 2 − 2.37 X 2 2 + 0.83 X 3 2 + 0.26 X 1 X 2 − 0.21 X 1 X 3 + 0.51 X 2 X 3, where Y is the measured biomass (g/L).
In this experiment, we tested for inducible costs of resistance, by applying multiple parasite exposures.
Our microsatellite data from northern Eurasian cattle populations empirically indicate a practical approach for identifying the best candidate loci under hitchhiking selection by simultaneously applying multiple neutrality tests based on different assumptions and parameter estimations.
After using a Spearman correlation test followed by applying a multiple testing correction at a FDR of 5%, we found 1,847 genes to be positively correlated and 1,445 genes to be negatively correlated with TWIST1 mRNA expression (Additional file 3: Table S9A, B).
We then performed a targeted analysis of cytokine genes by applying the multiple testing procedures to this subset after RMA processing was completed.
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