Sentence examples for by applying a stringent from inspiring English sources

Thus, the meaning of collected data needs to be carefully scrutinized by applying a stringent systemic approach which accounts for the ecological context of the investigated organisms.

We investigated whether the rates of false positive detection could be improved by applying a stringent threshold to the log2 ratios, as reported in Cahan et al. [6].

Z-scores are discretized by applying a stringent threshold Θ0.01 corresponding to an E-value of 0.01.

By applying a stringent cut-off threshold 2,060 genes were identified as being differentially expressed in at least one of the respective carbon source comparisons.

The intuition is that by applying a stringent sequence similarity filter, we can remove the vast majority of evolutionarily unrelated genes.

By applying a stringent threshold induction ratio of 3-fold, we restricted the analysis to genes with a robust transcriptional induction in mycorrhizal roots.

Therefore, selection was performed by applying a more stringent criterion, where only those genes with differences in expression levels having a p value of less than 0.01 and a two-fold variation being selected.

Specifically, by applying a very stringent post-imputation QC threshold, a smaller set of variants with more accurately predicted genotypes remain.

Furthermore, by applying a more stringent PCA based approach, 36 CpG loci sufficient to differentiate between PCNSL and hematopoietic controls in a highly significant fashion have been identified.

We tested the extent of hearing loss by applying a more stringent threshold of greater than 40 dB for defining hearing loss in the worst affected ear.

The majority of these transcripts are found within the lower intensity range and we therefore tested if meaningful information could be extracted from this region by applying a more stringent selection.