Sentence examples for by analyzing mouse models from inspiring English sources

The role of BH3-only proteins in normal physiology has been addressed primarily by analyzing mouse models lacking the individual genes (7).

By analyzing mouse models generated by chromosome engineering to obtain different dosages of genomic interval D4Mit190-51, whicorrespondsnds to human 1 p36, Bagchi et al. demonstrated that CHD5 was the leading tumor suppressor gene in this interval [ 2].

However, data obtained by analyzing transgenic mouse models in respect to alterations in sulfatide levels are more inconsistent.

Research into the etiology of KD/SBMA has been hampered somewhat by mouse models being analyzed individually, with little or no direct comparison between models.

To study regulation of WNT11 by VHL, we analyzed mice lacking Vhl in specific tissues.

By analyzing metabolic pathways in numerous mouse models of cancer and in human cancer samples transplanted into mice, the team found that the browning of white fat "was consistent in all of these models and led irreversibly to cachexia," says study co-author Erwin Wagner, a cancer biologist at CNIO. "This process is likely happening in these patients.

To address this question, we have analyzed two transgenic mouse models: APP48 and APP23 mice.

We therefore attempted to define the pathological and/or protective mechanism in our JEV-infected mouse model by analyzing the relative expression levels of each TCR family and the T-cell clone frequency.

Prompted by reports on the ERE-independent estrogen activity of Cd (Siewit et al. 2010: Zhang et al. 2007) and by our observations of the estrogen-like ERE-independent activity of Cd in the uterus, we explored the possible involvement of nonclassical ER signaling in Cd-mediated responses in our mouse model by analyzing pErk, pAkt, and pMdm2 contents in liver homogenates.

In order to map genes controlling susceptibility to PIFS in the B6 × 129S1 F2 model, we constructed a genetic linkage map of the mouse genome by analyzing 273 randomly selected mice using Illumina Chip Technologies.

Table 1 Function of Atg7 revealed by genetic mouse models.