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Cox regression analyses will be used to investigate the intervention effect, by analysing differences in outcome with survival analysis of the primary outcome measure between the MISS and usual care group.
This hypothesis is testable through investigation of gut-barrier function in children suffering from malaria, characterisation of the cytoadhesion profile of clinical parasite isolates from children with malaria and endotoxaemia and by analysing differences in the innate and adaptive immune response pathways in children with severe malaria in the presence or absence of endotoxaemia.
By analysing differences in trends in clinical trial registration between countries and regions, the study shows that increases in trial registration have had different trajectories in different parts of the world, and that a coalescence of global and local measures is needed to increase the proportion of trials that is registered in countries.
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Subsequently, construct validity was determined by t-tests and effect sizes (es), analysing differences in PedsQL scores (per age group) between healthy and chronically ill children and between children that did or did not visit their general practitioner, medical specialist or psychologist over the past year.
Patients were stratified by log(SFRP4) tertiles to analyse differences in baseline characteristics using ANOVA for continuous and Fisher's exact tests for categorical variables (Table 2).
We intended to analyse differences in outcomes by conducting adequate randomisation, allocation concealment and blinding.
In the descriptive analyses, differences in covariate values by type of dietary pattern (vegetarian, semi-vegetarian, nonvegetarian) were assessed by ANOVA and by χ tests for categoric data.
We can therefore create an ODF by analysing the differences in peak amplitude values over consecutive frames.
This can be shown specifically by analysing the differences in gene induction; for example hac1 and der1 are above the twofold change threshold in the secretion strain at 2.23 and 2.02, but below the threshold in the intracellular strain at 1.45- and 1.73-fold.
By analysing the difference in labour market outcomes in regions with different attitudes towards immigrants, we intend to test discrimination in a more direct way.
The effect attributable to the intervention will be assessed by analysing the difference in the changes between the groups, and 95% confidence intervals will be calculated, adjusting the values for the baseline levels, using analysis of covariance (ANCOVA).
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