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Gram testing was done by adding a drop of 3% w/v aqueous KOH to a sub-sample of the colony on a microscope slide and confirming the presence of Gram negative isolates by an observed increase in viscosity.
However, unexpectedly, both cell lines showed a smear of higher molecular weight bands suggestive of PARP hyperactivation, which was subsequently confirmed by an observed increase in poly(ADP-ribose) polymers.
This was supported by an observed increase in the percentage of IFN-γ positive CD8hi cytotoxic T cells as well as IFN-γ positive CD8-/low helper T cells after PCV2 in vitro re-stimulation.
A strong ER stress response to Tn resulted in the activation of inflammatory cytokines (IL-1 β, IL-6) and a robust microglial response (MCP-1/CCL2) that was confirmed by an observed increase in the number of IBA-1-positive cells.
The use of i.v. ATO is inconvenient, as it requires frequent patient visits for administration and maintenance of vascular access, further complicated by an observed increase in the rate of central venous catheter-associated thrombosis among APL patients compared with acute lymphocytic leukemia and AML patients.
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The study was closed prematurely (after enrolment of 171 of the planned 340 patients) by the Independent Safety Monitoring Committee following an observed increase in the number of adverse events and deaths in patients receiving placebo.
Mutations that produce an observed increase in activity by >1.3x in one background but not another are judged to be epistatically modified.
An increase in baroreflex sensitivity (as suggested by the observed increase in LF/HF ratio might be expected to be accompanied by a reduction in heart rate, though within our data this was not observed.
Indole derivatives promoted at high dietary levels aflatoxin B1 initiated hepatocarcinogenesis in rainbow trouts, an effect which was explained by the authors by the observed increase in estrogenic activities and induction of P450 isoenzymes [36].
This higher amplitude could be explained by a higher expression of GABA receptors in OM neurons, reflected by the observed increase in GABRA1, B1 and B2 receptor subunit expression, or by altered subunit composition of the receptors, resulting in a change in the physiological channel properties.
Notably, the prediction for increased CDKN2A protein abundance was also supported by the observed increase in CDKN2A mRNA levels in the test data set.
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by an observed decrease
by an observed shift
by an observed excess
by an observed mortality
by an observed correlation
by an observed cracking
by an observed role
by an observed absence
by an observed anomaly
by an observed sample
by an observed suppression
by an observed depolarization
by an observed loss
by an observed co-association
by an observed reduction
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com