Sentence examples for by an initial burst from inspiring English sources
The release profiles of ZP from microparticles were in general biphasic, being characterized by an initial burst effect and a subsequent slow ZP release.
The release of PDGF was bi-phasic, characterized by an initial burst followed by a period of sustained release for up to 21 days.
The release behavior was characterized by an initial burst and a second stationary phase, which enables the use of particles for long-term delivery.
A Korsmeyer-Peppas (r = 0.99; n>1 = 1.07) fitted kinetics typified by an initial burst release of 49.4 ± 1.9% at 4 minutes and a total of 99.8 ± 3.3% at 30 minutes was noted.
The redistribution of pyrene and perylene among arborescent micelles was studied by the fluorescence resonance energy transfer (FRET) technique, and was characterized by an initial burst in exchange followed by gradual equilibration of the probes.
Physostigmine release from the microparticles showed a biphasic pattern, characterized by an initial burst release followed by a sustained release for PLGA 65 35, PLGA 50 50 and RG 502 or a non-detectable release for PLGA 85:15, PLGA 75:25 and PLA.
Efficient regulatory function requires an initial burst, followed by consumption, of endogenous IL-2 followed by the release of other soluble factors such as IL-10 and/or TGFβ and IL-35 [ 10- 13].
In this study, the BR pattern was similar to those described previously by Pane et al. [26] and Cytrin et al. [32] with an initial burst of activity induced by compost, followed by a significant decrease approaching levels of the not-amended soil.
Graphs of protein release from scaffolds showed an initial burst followed by a slower sustained release.
In vitro release data indicated that SSGMS and GMS follow first-order release kinetics and exhibited an initial burst followed by slow release of the drug.
Thus, the design of the delivery systems with CUR as a model drug featuring dual release process – an initial burst followed by sustained release – to provide the optimal drug pharmacokinetics in the therapeutic region has been actively pursued.
