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These latter findings can also be partly explained by an induced decrease in blood glucose levels.
Cyclotoxic effects of flavopiridol may be also potentiated by an induced decrease in the stability of the mRNA of the antiapoptotic protein Bcl2.
With miglitol administration, all the subjects exhibited an attenuated postprandial increment in insulin, which may be explained by an induced decrease in blood glucose levels.
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To further confirm melatonin anti-angiogenic activity suggested by the induced decrease of VEGF levels under hypoxia, HUVECs tube formation assay was performed.
Catabolism is potentiated by a sepsis-induced decrease in amino acid uptake in skeletal muscle.
These disturbances, based on in vitro experiments, can be explained by a DEHP-induced decrease in aromatase mRNA and protein levels, causing decreased conversion of testosterone to estradiol (Lovekamp-Swan and Davis 2003).
We conclude that systemic chemotherapy may induce MSI and loss of heterozygosity in peripheral blood mononuclear cells from breast cancer patients receiving alkylating agents, possibly mediated by a chemotherapy-induced decrease in the expression of hMSH2.
Studies of the intestinal proteome suggest that the intestinal maladaptation in preterm neonates can be explained by a feeding-induced decrease in intestinal metabolism and stress response [ 8, 10], but the molecular mechanisms remain unknown.
On the contrary, therapy by both clarithromycin and amikacin induced decrease of the total caspase-3 activity of monocytes.
β2 blocking could be detrimental by counteracting a β2-induced decrease in platelet activation and improved fibrinolytic activity.
Moreover, potential protective effects of volatile anesthetics depend on energy-dependent signal transduction, e.g. protein synthesis and phosphorylation [35], that may be affected by hypothermia-induced decrease of global metabolic rate as well as suppression of protein synthesis.
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