As a consequence, cellular free cholesterol content drops, which, in turn, provokes a compensatory SREBP-2-mediated induction of cholesterol synthesis [32], [33] that is reflected by an increased expression of cholesterogenic genes and increased cholesterol synthesis.
When first considering the differentiated control, mRNA levels of Cebpβ and Cebpδ both increased after day 1, followed by an increased expression of Srebf1a.
However, the Antarctic octopod, Pareledone charcoti, was shown to mitigate this detrimental effect by an increased expression of a haemocyanin with lowered affinity for oxygen, and an increased rate of pH dependent oxygen release.
We have recently shown that the epidermal hyperplasia induced by topical retinoids was accompanied by an increased expression of CD44 and hyaluronate synthases and associated with an increase in epidermal and dermal HA in mouse skin [7].
This increased adhesion is likely mediated by receptors on the microparticles or by an increased expression of adhesive monocyte receptors (for example, CD11b, CD31) and may be further augmented by the expression of chemokines such as CCL5.
An enriched nitrergic neuronal population, evidenced by an increased expression of neuronal nitric oxide synthase, was obtained in tissue engineered sheets that included collagen IV.
To determine whether decreased estrogen receptor alpha (ER-α) expression in endometriotic lesions could be balanced by an increased expression of estrogen receptor-related receptors (ERRs).
By contrast, pathological muscles are characterized by a broad distribution of mitochondrial markers in all fiber types, not related to intrinsic features of double muscle phenotype and by an increased expression of sarcolemmal calcium extrusion pump.
Importantly, they exerted superior chondrogenic differentiation potential compared to previous FN-PAM-PLGA-TGF-β3, as shown by an increased expression of specific cartilage markers such as cartilage type II, aggrecan and COMP.
Conclusion: Chorioamnionitis was associated with an intrauterine inflammatory response of the fetal lung characterized by a severe infiltration of macrophages, neutrophils, and lymphocytes and also by an increased expression of interleukin 8 messenger ribonucleic acid.
Exposure of cells to insulin activated UPR, as evidenced by an increased expression of GRP78, XBP-1, phosphorylated PERK (p-PERK), and p-eIF2alpha.
