The work demonstrated an effective strategy for ameliorating α-ketoacid reduction pathway to produce C5 dicarboxylic acids, as well as the potential of integration of bioprocess and metabolic engineering for enhancing chemicals production by an engineered microorganism.
In a novel example of a system-wide metabolic engineering approach, the existing biological system was redesigned by an engineered reversal of the β-oxidation pathway in E. coli, leading to a significant increase in the production yield of carboxylic acids (Dellomonaco et al., 2011).
Konermann, S. et al. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Ring, A. M. et al. Adrenaline-activated structure of beta2-adrenoceptor stabilized by an engineered nanobody.
The configuration is stabilized by an engineered disulfide crosslink.
This study investigated conversion of acetic acid (HAc) to FAs by an engineered Escherichia coli strain.
In this report, BT is biosynthesized by an engineered Escherichia coli from d-xylose.
Prier, C. K., Zhang, R. K., Buller, A. R., Brinkmann-Chen, S. & Arnold, F. H. Enantioselective, intermolecular benzylic C H amination catalysed by an engineered iron-haem enzyme.
The laser beam was homogenized and expanded by an engineered diffuser (EDC10-A-1r, RPC Photonic), thereby resulting in a 2-cm-diameter illumination area on the object.
Eigenbrot, C., Ultsch, M., Dubnovitsky, A., Abrahmsén, L. & Härd, T. Structural basis for high-affinity HER2 receptor binding by an engineered protein.
Our process uses bacteria to convert waste gases into acetic acid — vinegar — which is subsequently converted to oil by an engineered yeast.
