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Mechanistically, these compounds do not inhibit the cruzain, but induce T. cruzi cell death by an apoptotic process.
Mechanistically, these compounds do not inhibit the cruzain, but induce T. cruzi cell death by an apoptotic process, being considered a good starting point for the development of new anti-Chagas drug candidates.
Mechanistically, the compounds inhibit cruzain, and 14 induces T. cruzi cell death by an apoptotic process, being considered a good starting point for the development of new anti-Chagas drug candidates.
This suggested that high-VT ventilation with room air or hyperoxia can induce lung injury by an apoptotic process.
Cell death by an apoptotic process is a well-described phenomenon that is associated with multiple molecular events.
It has been shown that the atretic process begins with cell death in the membrana granulosa initially by an apoptotic process [ 10].
Similar(51)
To investigate whether an apoptotic process demonstrated by 99mTc-annexin-V (99mTc-AV) uptake correlates with left ventricular remodeling (LVR) after myocardial infarction, we assessed 99mTc-AV uptake in rat model of myocardial ischemia and reperfusion.
Threshold level of IPC induced an apoptotic process, characterised by cell cycle arrest, hypercondensation of chromatin, an appearance of lobbed nuclei; abnormal, multipolar mitotic spindles, post-mitotic micronuclei formation due to nuclei fragmentation in the root cells of sensitive lines.
Although the aetiology is unknown, it has been suggested to be an apoptotic process mediated mainly by CD8-positive T lymphocytes, and viral or autoimmune factors are believed to be involved [ 1, 3].
Alternatively, ookinete invasion may not systematically lead to an apoptotic process, as also suggested by Shiao et al. [9].
Our study also demonstrated that upon PL injection, the formed tumors by inoculating DU145 or PC3 cells into nude mice underwent a regression, by triggering an apoptotic processes.
Related(20)
by an electromagnetic process
by an apoptotic response
by an additive process
by an unfair process
by an electrospinning process
by an historical process
by an automatic process
by an arbitrary process
by an opaque process
by an electrokinetic process
by an independent process
by an apoptotic mechanism
by an identical process
by an inductive process
by an individual process
by an inverse process
by an aqueous process
by an evolutionary process
by an iterative process
by an asexual process
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com