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Only recently, a study performed in a large mildly selected cattle population from Western Africa under an extensive breeding system has shown that LD extends over shorter distances than the previous studies from developed countries, which was explained by increasing selective pressure and/or by an admixture process (Thevenon et al. 2007).
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Third, a low variance is characteristic of an admixture process that occurred as a single event, whereas higher variance occurs when admixture is ongoing.
Extending a mechanistic admixture model to accommodate the X chromosome, we demonstrate that this prediction is not generally true in admixture models, although it holds in the limit for an admixture process occurring as a single event.
Our study has uncovered evidence of population stratification in Uruguay with likely roots in an admixture process that involved parental African, Native American and European populations.
This scenario corresponds to an admixture process in which populations S1 and S2 found the hybrid population H at the first generation and contribute little in subsequent generations.
In contrast, European wild boars, as well as local Mediterranean breeds like the Iberian breed, were not affected by this admixture process.
In addition, our findings suggest that the ancestral genome structure generated by the admixture process influences DNA methylation patterns, and underscore the importance of considering genetic ancestry as a modifying factor in epigenetic association studies in admixed populations such as Latino ones.
In this article, expanding on the models of Ewens and Spielman (1995) and Guo et al. (2005), we develop a general mechanistic model of a historical admixture process.
What patterns are expected for X chromosomes and autosomes in an admixed population formed through a sex-biased admixture process?
As we will show, however, it presumes a very specific history for the admixture process, a history often not viewed as reasonable for practical admixture scenarios.
In our software, Xplorigin, the admixture process is described by a top-level HMM that designates population ancestry in each region of the genome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com