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In particular, the maximum glucan conversion yields reached for AFEX pretreated NW and EA pretreated NW were obtained by an additive effect of the α-l-arabinofuraosidase rPoAbf F435Y/Y446F and the endocellulase rCelStrep, respectively, in addition of the array of (hemi cellulase activities present in the commercial mix.
The PRS approach relies on the theory that heritability, i.e. the amount of phenotypic variation explained by genetic components, of complex traits, is caused by an additive effect of multiple common gene variants with small effect sizes, a so-called polygenetic effect that is traditionally identified by GWAS.
The PCI of scFvMEL/rGel treatment was found to act in a synergistic manner (p<0.05) as compared to the expected sum of the individual treatments scFvMEL/rGel and PDT with R = 1.15, indicating that the tumor growth delay by PCI of scFvMEL/rGel was more that twice as long as expected by an additive effect.
OVA-specific memory plasma cells (CD138+κλhi) were also significantly reduced by an additive effect on JAK and SYK signaling (Fig. 7f).
This effect can also be accounted for by an additive effect in intensity of the mixture in cases where both constituents show gradual increase in pleasantness as a function of their intensity.
All of the reductions observed in the ethanol-treated mutants are far beyond that predicted by an additive effect of ethanol-treatment in wild types and loss of pdgfra without ethanol.
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Combination therapies utilising rapamycin plus a drug acting on an mTOR independent pathway may provide more effective treatments for neurodegeneration by providing an additive effect on autophagy induction while reducing the adverse side effects of rapamycin treatment alone.
Reads mapping to overlapping regions between multiple transcripts were assigned to unique transcripts based on information from the uniquely mapping portion of each transcript and by assuming an additive effect of the read depth in the overlapping regions.
We briefly entertained the alternative hypothesis that the reduction in wing size generated by coexpressing UAS.dSno, an additive effect rather than Wg antagonism, was responsible for rescue of UAS.Dsh lethality.
The increased utilization of cholesterol for bile acid synthesis engendered by BAS, coupled with the continued strong inhibition of the rate-limiting enzyme in cholesterol biosynthesis by statins, produces an additive effect upon LDL-receptor protein synthesis and a further lowering of serum cholesterol.
Antagonistic effect was indicated for almost all the two-compound and three-compound combinations at 50% effective dose for H460/TaxR cells, except an additive effect by 107 167 combination and a moderate synergism by 27 167 254 combination.
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