Furthermore, while both Vβ-to-Dβ and Dβ-to-Jβ are allowed by B12/23 restriction, an additional level of regulation ensures an ordered V(D J recombination at the TCRβ locus, with Dβ-to-Jβ joining occurring before Vβ-to-DJβ gene assembly [25] (Figure 1B).
Specifically, before being undertaken using funds from the HHS, proposed studies that are reasonably anticipated to generate H7N9 viruses with increased transmissibility between mammals by respiratory droplets will undergo an additional level of review by the HHS.
Transcriptional regulation of flavonoid biosynthesis structural genes are controlled by regulatory genes, which provide an additional level of control.
Our data demonstrating functional cooperativity between effectors delivered by separate T3SSs hints at an additional level of unexpected complexity.
One more TLS-positive tumour was identified by staining for TLSs at an additional level about 100 μm deeper in the tissue blocks from 45 of the patients.
Therefore, mRNAs with expanded CAG repeats could induce toxicity on an additional level: by the production of polyQ, polyS or polyA proteins, all of which might be linked to disease pathology.
The potential expression of a soluble CD244 variant suggested by this study, may introduce an additional level of regulation of lymphocyte interactions in non- C57BL/6J -related strains, and may therefore contribute to immunological differences between C57BL/6J and other strains.
In a recent study, a few AtCBL members were also found to target to another group of enzymes 5'-methylthioadenosine nucleosidases by yeast two-hybrid system, indicting an additional level of complexity on the CBL-mediated signaling networks [ 26].
"I always wanted to achieve an additional level of freedom by making it possible to interact with the projection itself.
Finally, we introduce an additional level of stringency by requiring a minimum frequency of MCD in the given cohort.
