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The scar is created by an abnormal form of healing following this dermal inflammation.
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Protein induced by vitamin K absence or antagonist II (PIVKA-II), an abnormal form of prothrombin, has been used as an aid in the diagnosis of hepatocellular cancer (HCC) as a tumor marker.
They are characterized by prolonged incubation periods and distinctive neuropathology that includes deposition of an abnormal form of the prion protein (PrPSc), spongiform change, gliosis and neuronal loss.
In 1997, however, a team led by neurologist John Collinge of St. Mary's Hospital in London found an abnormal form of the prion protein (PrP), which is the signature of vCJD, in the tonsils of a deceased patient.
The disease is caused by a mutation in the ' huntingtin' gene, which leads to the production of an abnormal form of 'huntingtin' protein.
Experts believe the disease is linked to contaminated feed made from meat and bone meal that contains an abnormal form of a protein called a prion.
Patients with Grade 3 gliomas whose tumors had an abnormal form of the protein called epidermal growth factor receptor lived a median of only 7.2 months, compared with 33 months for those with the usual form of the protein.
Previous work by the Prusiner team and others had shown that prions consist of a cellular protein that has misfolded into an abnormal form.
Gross et al. [69] interpreted H. citrinus as an abnormal form of H. olivaceus.
Namely, an abnormal form of these proteins once formed in cells promotes the conversion of monomeric normal protein to an abnormal form.
Thus, we consider that this labelling represents an abnormal form of PrP labelling.
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