Sentence examples for by an abnormal activation from inspiring English sources

This possible mechanism was explained therein according to an excessive sympathetic reaction, causing an opposite reaction to the initiated by an abnormal activation of mechanoreceptors activation, and also causing the activation of the afferent vagal fibers.

TTP is caused by a hereditary (genetic) or acquired (autoantibodies) ADAMTS13 deficiency, whereas aHUS is caused by an abnormal activation of the alternative complement pathway due to defective regulation of specific complement factors [ 50, 61– 63].

Indeed, sporadic AD is characterised by an abnormal activation of the endocytic pathway, with associated increases in PI3K and RAS signalling and Rab5 levels, and comprises early neuropathological alteration even before A β pathology ensues [ 39– 41].

Taken together, the findings indicate an abnormal activation of the HPA-axis in abdominally obese women.

In these mice, hepatocytes were hyperproliferative and displayed an abnormal activation of Akt [ 117].

Figure 5 demonstrates that the suppressive effect of mature α/β TCR transgenes on DN cell proliferation is mediated by the abnormal activation of PKD2 catalytic activity.

Autoimmune diseases may be initiated by malfunctioning lymphocytes whose apoptotic pathways, normally activated by self-antigens, are blocked by abnormal activation of NF-κB, enabling the survival of self-reactive cells [ 21, 127- 130].

Further experiments suggested that the reaction was caused by the abnormal activation of certain genes in the iPS cells, resulting in the production of proteins that seemed foreign to the immune systems of the mice.

Currently, no ideal treatment for ALCL caused by the abnormal activation of ALK and its downstream signaling pathways is available.

This effect is likely triggered in part by abnormal activation of liver endothelial cells as suggested by Yan et al and Wu et al [23], [41].

Next, we investigated whether the characteristics of CSLCs in tumorspheres were maintained by abnormal activation of the SHH pathway.