Sentence examples for by altering their functions from inspiring English sources

Although the mechanisms underlying the regulation of these cytokines in the kidneys of patients with diabetes mellitus remain unclear, it has been proposed that genetic variations in the genes encoding the inflammatory cytokines might confer susceptibility to DN [10] by altering their functions or expressions.

For examples, PKR inhibits cellular mRNA translation which in turn prevent viral protein synthesis [ 20] while ISG15 achieves its antiviral function by conjugating to target proteins followed by altering their function [ 21].

Since single nucleotide mutations occurred within the stem regions as well as mature miRNAs are important evolutionary powers for driving the production of new miRNAs by altering their biological functions (Sun et al. 2009), it is very intriguing to further uncover the SNPs characteristics and their possible effects on miRNAs evolution in the rice genome.

Since miRNAs are small functional units, single nucleotide shifts in the precursor elements as well as the mature miRNA sequences may drive the evolution of new miRNAs by altering their biological functions [ 37].

Polymorphisms in the genes encoding these enzymes, by altering their expression and function, may increase or decrease carcinogen activation/detoxification, followed by modulation of cancer risk [ 15, 16].

Thus, a plausible explanation for our findings would be that traffic-related air pollution may increase mortality in heart failure patients by altering their cardiac autonomic function.

The function of enzymes can be regulated by altering their kinetic properties, whereas the function of nonenzyme genes is regulated primarily by altering their expression levels.

Therefore, MD affected neurons belonging to the CB class by altering their neurochemistry and possibly also their functioning, but it is not known whether it also changed their visual responsiveness.

Mammalian cells control their shape and function by altering their mechanical properties through structural rearrangements and changes in molecular biochemistry at the nanometer scale.

Here, we show that disulfiram is able to alter the sub-cellular localization of endo-lysosomal components and by this mechanism may alter their function, providing more evidence that the lysosomal sequestration of zinc may promote lysosomal disruption.

We remedy it by altering the above function as f(n, x) = x*n.