Sentence examples for by altering the stability from inspiring English sources

Our studies suggest a mechanism by which cytoplasmic factors can modulate channel gating by altering the stability of the helix D coiled-coil, thereby influencing CaM-dependent PIP2 regulation32.

In some bacteria, Hfq has proved to influence the expression of virulence genes by altering the stability of their mRNAs [26], [28] [31].

However, we have not yet ruled out that Ago2 might also regulate gene expression at the protein level by altering the stability or overall activity of the protein.

miRNA regulating target gene expression by altering the stability of the transcript and/or interference with the translational process adds another level of complexity that must be considered in dissecting the complex cascade of events that follow nerve injury during and after the development of chronic pain.

First, CG-1521 may reduce transcription by altering the stability and/or activity of nuclear proteins including transcription factors.

miRNAs interact in several ways with target mRNAs, and may exert non-canonical regulatory actions, but they commonly act post-transcriptionally by altering the stability of target mRNAs.

Three distinct binding mechanisms are realized by altering the stabilities of the individual monomers: docking, coupled folding-binding of a single α-helix, and synergistic folding and binding.

In conclusion we have demonstrated that the structural element responsible for GSTM2 cell translocation is the C-terminal globin-like domain and that gains in cell translocation efficiency may be achieved by altering the conformational stability of this domain.

It has been shown that earthworms influence the resistance of plant communities against plant invaders and this effect varied with plant diversity and with time [ 11, 20], possibly by altering the diversity-stability relationship.

While we caution against drawing general conclusions from this analysis, our results suggest that climatic change has the potential to influence the stability of this community by altering the dynamics and stability at any single, or all three, of the individual trophic levels.

Importantly, altering the stability of the C-terminal domain of apoE4 by the above mutations does not decrease lipid binding to that exhibited by apoE3.