Sentence examples for by altering the sequence from inspiring English sources

The efficiency of the MABS technique was demonstrated by altering the sequence specificity of the bifunctional RE Eco57I from 5′-CTGAAG to 5′-CTGRAG, and thus generating the mutant restriction endonuclease (and DNA methyltransferase) of a specificity not known before.

Structure activity relations (SARs) were designed to help explain the significant difference in activity observed among the catalysts containing monometallic (Ni) and bimetallic species (Ni Co) and among the bimetallic catalysts impregnated by altering the sequence of impregnation.

Although the majority of hER-E/F protein was produced in insoluble form under standard bacterial culture conditions, hER-E/F could be produced in soluble, biologically active form by altering the sequence of the expressed protein and by varying the host culture conditions.

The tuning of the computational units (i.e., ribozyme and the receptor sites) is achieved by altering the sequence of bases in certain regions of the nucleic acids guided by energetic information that can be calculated from the sequence to structure mapping of the molecules.

Genome editing can be used to study protein function by altering coding sequence or achieve transcriptional control by altering the sequence of regulatory regions.

For both, the concentration of the pseudoknot required for the titration can be manipulated by altering the sequence and length of the competition strand.

The sequences important for target site recognition, as determined for Eh EN [ 18], were tested for Ed EN by altering the sequences immediately surrounding the nicked site #3.

Nevertheless, by artificially altering the sequence of the yeast telomeres in such a way that Rap1 binding is lost, though slightly shorter, the telomeres are stably maintained in dividing cells, and TEL1 deletion affects their length similarly to wild-type cells [ 174– 174].

We found that, like rats, female mice do pace their copulatory behavior by altering the temporal sequence of copulatory events.

The average mesh size can be modulated by simply varying the concentration of a given peptide used to construct the gel or by altering the peptide sequence.

It has also been shown that the compressibility and distortion of the softer LiO6 octahedra can be controlled by altering the stacking sequence of the more rigid covalently bonded octahedra.