Sentence examples for by altering the microenvironment from inspiring English sources

By changing their phenotype or by altering the microenvironment tumor cells can evade therapies.

Macrophages may contribute factors that affect tumor progression by altering the microenvironment including angiogenic and proteolytic factors [ 19].

3 5 Moreover, Jund-mediated oxidative stress has played a pivotal role in systemic regulation of insulin that affects lifespan and in tumor development by altering the microenvironment.

Forcing adult cells to change lineage by altering the microenvironment offers an alternative to the more risky method of virus-mediated nuclear reprogramming [ 6, 7].

Indeed, it is now recognized that inflammatory responses, similar to those associated with wound healing or infection, support the development of invasive carcinomas by altering the microenvironment in favor of proliferation, cell survival, angiogenesis and tumor cell dissemination while also disrupting antitumor immune surveillance mechanisms.

Bacterial communities associated with the skin of amphibians may protect the host from pathogens (i) by increasing competition for space and resources, (ii) by altering the microenvironment of the amphibian skin to prevent colonization of pathogens, and (iii) through the production of antimicrobial metabolites that kill or inhibit the growth of pathogens (2 – 4).

In general, our study suggests that the silicate bioceramics could regulate immune responses by altering the ionic microenvironment between the implants and hosts, which may offer new insight about the mechanism of the bioactivity of silicate bioceramics in bone regeneration and provide profitable guidance for designing new biomaterials for bone tissue engineering.

We propose that it may be possible for future AD therapies to promote the maturation of functional stem cell-derived neurons by altering the brain microenvironment with trophic support and by targeting different aggregation forms of Aβ.

MSCs protect against injury by altering the oxidative microenvironment of the liver.

For instance, irradiated fibroblasts are known to promote tumor formation in neighboring epithelial cells by altering the tumor microenvironment [ 18].

These enhanced antitumor efficacies functioned by altering the intratumoral microenvironment, limiting tumor angiogenesis, inducing tumor cell apoptosis, and infiltration of lymphocytes.