Sentence examples for by altering the functional from inspiring English sources
If a molecule should inhibit viral growth by altering the functional properties of the virus (viral structure or surface glycoprotein), infection would be inhibited in the preincubated virus condition but not in the preincubated cells one.
This model is based on the notion that agents that alter the activity of orthograde coupling by altering the functional state of RyR1 may affect retrograde signaling and vice-versa.
On physiological terms, our model of benign thyroid disease considers magnesium deficiency as a condition that leads to mitochondrial dysfunction by altering the functional integrity of Complex V of oxidative phosphorylation (OXPHOS).
These might act in a variety of ways to modify the sesB phenotype – e.g. by altering the functional properties of the OXPHOS system, the architecture of the inner mitochondrial membrane or the output of mitochondrial protein synthesis.
Moreover, integrin-linked kinase can stimulate Akt activity via PI3-K, and this in turn can influence murine MEC survival by altering the functional status of BAD [ 10, 15].
Various nanogel properties can be attained by altering the chemical functional groups, cross-linking density, and surface-active and stimuli-responsive elements [ 58].
By adjusting the size and altering the functional end-groups of the dendrimers, the effective diameter, molecular weight, and hydrophilicity can be varied [ 50– 50].
The structure of Compound 2 was optimized by retaining the intact thiazolidione core structure and altering the functional groups.
Unlike well characterized riboswitches in cellular RNAs, the control of infectious RNA activities by altering the configuration of functional RNA domains has only recently been recognized.
Progress was achieved by altering the B3LYP DFT functional (B4 XQ3 LYP-approach) and supplementing it with an empirical correction term, which is applied after the quantum-chemical DFT computations.
It has been hypothesised that a local imbalance between coagulation and fibrinolysis contributes to pathogenesis, and it is possible that autoantibodies targeting citrullinated fibrinogen could contribute to this imbalance by altering the structural and/or functional properties of fibrinogen and/or fibrin.
