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Animal studies and protein modeling suggest that the Ile655Val polymorphism located in the transmembrane domain of the HER2 protein might influence breast cancer development by altering the efficiency of homodimerization.
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An important limitation of microarray technology for studying insecticide resistance is its inability to identify mutations in detoxification enzymes that may confer resistance by altering the metabolic efficiency of the enzyme for insecticides.
In the case of transcriptional regulators, such as zinc finger proteins that contain POZ domains, these domains mediate transcriptional repression through recruitment of co-repressor proteins or by altering the binding efficiency between the zinc finger domains and the target DNA (Chang et al. 1996).
By altering the container loading efficiency it was possible to develop an understanding of influencing factors on forces subjected to a loaded container.
The scenarios were designed by altering the reproductive management efficiency and the status of reproductive physiology of the herd.
Such analysis is important because ethanol reduces its fuel production efficiency by altering the alcoholic fermentation step when in excess.
In several enzyme families, changes in the domain alliances are known to modulate the enzyme function, usually by altering the substrate specificity or enzyme efficiency.
Analysis of the hydrophobic moieties that induce high transfection efficiency by altering the alkyl chain lengths and the positions revealed that lipids with an amino residue attached to C12 in the meta-meta position exhibit the highest efficiencies [ 16].
The goal is to achieve additional structural efficiencies by altering the geometry of the roof structure while simultaneously optimizing the roof member and column cross-sectional dimensions and the roof topology.
Different colors and greater efficiency are created by altering the composition of the material.
The small variations that one sees are likely due to changing continental positions having an effect on the efficiency of marine photosynthesis, e.g. by altering the nutrient supply, and thus on the organic carbon burial rate.
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CEO of Professional Science Editing for Scientists @ prosciediting.com