Sentence examples for by altering localization of from inspiring English sources

Cadherins can also provide the ability to modulate the Wnt signaling pathway by altering localization of β-catenin in the cell [ 26, 35].

Similarly, null mutation of pex3 (node 45046) affects fatty acid oxidation (node 19395), possibly by altering localization of the PMP Pex11p [ 18].

Information from the STRING database [ 33] (gene neighbourhood and co-occurrence) allows us to functionally link Rv2717c with DNA repair and cell wall synthesis; NrdR is involved in the control of the synthesis of dNTP needed for DNA replication and/or DNA repair [ 69]; and the cell wall hydrolase Rv2719c is involved in suppressing the cell cycle by altering localization of FtsZ rings [ 70].

Activation of PKD induces membrane fission at the TGN, which can be monitored by altered localization of Golgi marker proteins by immunofluorescence (Bossard et al., 2007; Liljedahl et al., 2001).

Our findings point to the possible phosphorylation and altered localization of p300 by Braf/MAPK signaling, which needs further investigation.

The present experiments were designed to test the hypothesis that CD might function as a pro-apoptotic trigger by altering the localization of connexin 43 gap junction protein and gap junctional intercellular communication (GJIC).

It is important to note that B box barriers do not associate with Pol III and have been proposed to function by forming chromatin loops and/or by altering the nuclear localization of domains of chromatin, since dispersed sites of TFIIIC association coalesce at the nuclear periphery [22].

Ectodomain shedding affects the biological activity of membrane proteins such as growth factors, growth factor receptors, cell-adhesion molecules, and extracellular matrix proteins by altering their localization and mode of action [ 10].

We recently described altered localization, abnormal modification and loss of function of SigR1 in sporadic ALS.

Loss of the various Elo enzymes clearly affects the localization of α-syn, and the altered localization might underlie the enhanced toxicity of α-syn these strains.

Here we demonstrate a mechanism by which the intracellular, carboxy-terminal tail of polycystin-1 (CP1) regulates mTOR signaling by altering the subcellular localization of the tuberous sclerosis complex 2 (tumor tumor suppressor, a gatekeeper for mTOR activity.