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Dietary Na/K ratios were obtained by altering levels of Na2CO3 and K2CO3.
RPE cells, in expressing receptors for various cytokines [40], also respond prominently to cytokine signaling by altering levels of cytokine production and secretion, synthesizing nitric oxide [41], increasing adhesion molecule expression[42], and regulating RPE tight-junction integrity [43].
Ubiquitination of target proteins by Ubc4 could regulate SPB size by altering levels of SPB proteins or by affecting their incorporation into the pole, thereby changing the nucleation capacity of the SPB.
Given the elevated levels of KLK6 in MS patient serum and in active MS lesions we hypothesize one role may be to prolong inflammatory cell survival by altering levels of Bcl-2-family members.
Additional studies of various HDAC inhibitors in rodents have shown that HDAC inhibitors may act by altering levels of synaptic plasticity and in this context HDAC inhibitors have been used to modify learning, memory, and emotional behavior underscoring the potentially pleiotropic effects of targeting global levels of gene expression regulation [14], [15], [16], [17], [18], [19].
Organisms may adapt to new or changing environmental conditions by altering levels of gene expression.
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nSSL-BMS treatment leads to lower levels of cerebral inflammation, expressed by altered levels of corresponding cytokines and chemokines.
This suggests that PuF may exert anti-metastatic properties by, in part, altering levels of APP expression, reducing overall results of APP protein's ferroxidase activity and modulating cancer risk.
Atherosclerosis, as an inflammatory disease, is characterized by pathologically altered levels of cytokines.
Furthermore, retinoid uptake was strongly influenced by genetically and nutritionally altered levels of LPL expression [18].
In addition to NO suppression per se being not relevant in this context, arginine depletion by ADI treatment would alter levels of polyamines, proline, and glutamate.
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