Sentence examples for by altering activity of from inspiring English sources

To evaluate the effects of altered IIS on growth rate and the timing of metamorphosis, we began by altering activity of genes of the protein kinase A (PKA) pathway within the insulin producing cells (IPCs).

Significant associations represent variants that may have a direct effect on the transcription rate of nearby genes, likely by altering activity of cis-regulatory elements.

Polymorphisms in the GST genes, such as GSPT1 (rs1695), affect the ability to respond to excessive oxidative stress by altering activity of the GST enzymes [ 45].

Consumption of crude khat extract or its alkaloid fraction preceding stress has been shown to produce oxidative stress in rats by altering activities of serum antioxidant enzymes [ 6].

New research demonstrates that hypnosis can be used to overcome such cognitive conflicts by altering activity in specific regions of the brain.

Much interest has therefore centred on the roles of orthologous forkhead box O transcription factors in other organisms, including humans (Greer & Brunet, 2008; Partridge & Bruning, 2008; Greer et al., 2009), and in the mechanisms by which altered activity of daf-16 increases lifespan in the worm.

These small molecules act (i) directly, following their delivery to the mitochondrial matrix, the IMM or the OMM; or (ii) indirectly, by binding to and altering activities of transcription factors for nuclear genes encoding various mitochondrial proteins [ 34, 53- 61].

Silioxanes identified by GC-MS could alter activity of enzymes through specific or non-specific interactions.

This proteolysis by DPP-4-like activity can alter activities of target substrates, including the functional activation and inactivation of bioactive peptides or facilitated degradation of macromolecules by other peptidases [ 14].

Drugs may act directly on the smooth muscle cells, or they may act indirectly for example, by altering the activity of nerves of the autonomic nervous system that regulate vasoconstriction or vasodilation.

The rpn3 allele would have partial dominance by altering the activity of half of the proteasome particles.