Sentence examples for by altered patterns of from inspiring English sources
Endogenous expression of DUX4-FL was, however, accompanied by altered patterns of immunostaining for both Ub-proteins and TDP-43, and these alterations were similar to those seen upon exogenous DUX4-FL expression in myotubes.
Regulatory changes can occur through heritable sequence mutations or epimutations caused by altered patterns of DNA methylation, and there are examples of such mutations in both the coding regions of genes and associated transcription factor-binding regulatory elements that have had an historical impact on plant phenotype.
The cytoskeletal disorganization was accompanied by altered patterns of serine and tyrosine phosphorylation as well as changed expression and subcellular localization of integral signaling intermediates APC and PKCβII.
Individuals with MDD are characterized by altered patterns of DMN activity during emotion processing tasks as well as at rest.
The accumulated data suggest that many diseases and metabolic disorders are caused by altered patterns of gene expression (Kaminsky et al. 2006; Perini and Tupler 2006; Maekawa and Watanabe 2007).
However, in chronic human inflammatory conditions, such as chronic inflammatory demyelinating polyradiculoneuropathy and Crow-Fukase or POEMS syndrome, derangements of the BNI reflected by altered patterns of claudin-5 and ZO-1 immunostaining [ 54] and endoneurial immunoglobulin staining [ 146] may not be as readily self-limiting.
Taken together, these findings showed that RASSF9−/− mice suffered from a severe defect in epidermal homeostasis characterized by abnormal thickening of epidermis, dysregulated cellular proliferation, and disruption of keratinocyte maturation as revealed by the altered patterns of keratin and filaggrin expressions.
Moreover, these simulations identify the mechanisms by which altered patterns of STX/PIP2 interactions (e.g., due to K2A mutation or PIP2-depletion) result in the type of changes in accessibility of S14 that can modulate the phosphorylation of STX at that site.
It is conceivable that the rebuilding phase may occur indirectly through the effect of altered patterns of mechanical loading by increasing the production of growth factors (TGFβ1, IGF-1, bFGF), anti-inflammatory cytokines (IL-4) or soluble mediators (Substance P, glutamate) [ 56- 60].
The altered patterns of marker expression were accompanied by changes in the morphological appearance of the Li-7 cells.
This pattern reinforces the observation of altered patterns of unisensory processing in individuals with MCI.
