Sentence examples for by altered function of from inspiring English sources
Several cognitive symptoms commonly associated with severe AUD, ranging from poor risk management to the cognitive/affective dimension of pain, are probably mediated by altered function of key anatomical elements that modulate PFC executive function, including contributions from the cingulate cortex and insula.
The abnormal regulation of PI 3,5 P2 thus appears to be caused by altered function of the vac14-2 protein.
Early studies have suggested that the platelet hyperserotonemia of autism may be caused by altered function of SERT in blood platelets [ 27].
Rare Mendelian diseases are caused by altered function of single genes and individually have a low prevalence (fewer than 200,000 people in the United States, or fewer than 1 in 2,000 people in Europe) [ 4] but collectively these affect millions of individuals worldwide [ 5- 7].
In studies of working‐age adults, we have previously shown that psychosocial factors were strong predictors of new‐onset WP (17), and that the risks conferred by those factors were moderated by altered functioning of stress‐response systems, including the hypothalamic pituitary adrenal stress axis (49).
Nodal physiology is disturbed by altered function, localization, and expression of voltage-gated ion channels clustered at nodes and juxtaparanodes, and by disrupted axon glial interactions at paranodes.
The possible mechanisms by which altered function of NRG1 and its receptor ErbB4 contribute to schizophrenia have been reviewed by Mei and Xiong [ 211].
It is so far considered that the defects caused by these mutations result from altered function of cohesin in regulating gene expression during development.
Demonstration of a genetic association does not prove causality, which must be established by subsequent experiments showing the altered function of the gene and mechanistic impact in the disease.
The altered function of SDS stroma reported by Dror was demonstrated by in vitro experiments using BM stroma in toto as an integral unit of various cell types.
